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PhD position - 3D porous materials for the design of sequential fluidic bioreactors
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JOB DETAILS
Published: 20 days ago
Application deadline: Oct 31
Location: Grenoble, France
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PhD position - 3D porous materials for the design of sequential fluidic bioreactors

SL-DRT-18-1018

RESEARCH FIELD

Materials and applications

ABSTRACT

3D porous materials are currently used for their intrinsic structural properties that offers exceptional surface/volume ratio. This property allows rapid exchanges between a processed fluid and the macroporous surface. Moreover, the use of deformable (compression, stretching…) macroporous materials enables easy management of filling and the extraction of fluids through reduction or increase of the internal volume under mechanical stress. These deformable macroporous 3D structures represent a new class of materials of high interest for the design of electrochemical bioreactors. Indeed, the intrinsic open-porosity could be used for the confinement of biological species (enzymes or cells), transforming each pore into single microreactor. Moreover, this 3D macroporous structure could benefit from further implementation of electronic conductivity to the structural material to generate volume 3D electrodes. This thesis deals first with the development of conducting, biocompatible and deformable 3D macroporous-materials in the perspective of enzymatic or cell bioreactor design. These materials will bring original insights on in situ monitoring of cell cultures or on the design of highly sensitive biosensors. Thereby, in a second step the thesis will consist on the functionalization of the macroporous structures and on the design of the bioreactors. The applicant should presents a strong background on materials sciences (and especially macropourous deformable materials) and electrochemistry. Some knowledges on biology/biochemistry and microfluidic would be positive.

LOCATION

Département Nord Pas De Calais

Grenoble

CONTACT PERSON

REVOL CAVALIER Frédéric

CEA

DRT/DTBS/SBSC/LBAM

CEA-Leti, MINATEC Campus Département microTechnologies pour la Biologie et la Santé (DTBS) 17 Rue des Martyrs, F 38054 GRENOBLE Cedex 9, FRANCE

Phone number: 04 38 78 99 76

Email: frederic.revol-cavalier@cea.fr

UNIVERSITY / GRADUATE SCHOOL

Autre

Sciences pour l'Ingénieur (SPI) - Lille I -

START DATE

Start date on 01-10-2018

THESIS SUPERVISOR

PERWUELZ Anne

ENSAIT

GEMTEX Lab

GEMLaboratoire GEMTEX – EA 2461 – Université de Lille Nord-de-FranceEcole Nationale Supérieure des Arts & Industries Textiles (ENSAIT)2 rue Louise et Victor Champier BP30329, 59056 Roubaix cedex 1

Phone number: 03.20.25.64.69

Email: anne.perwuelz@ensait.fr

« The age limit is 26 years for PhD offers and 30 years old for post-doc offers. »

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